Adult Stem Cell Successes: 73 vs Embryonic Stem Cell Successes: 0
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Stem Cell Research

Stem Cell Cures         

The Right To Life Committee of New Mexico (RTLCNM) supports the use of stem cells for medical purposes, as long as the stem cells are not taken from an embryo, which then causes that human life to die. There has not been one cure ever established using embryonic stem cells, but there have been tumors and death from using these types of cells.

The University of Kentucky has coaxed stem cells from adult mice to change into brain, heart, nerve, and pancreatic cells mimicking embryonic stem cells. Now “a lot of people report the presence of embryonic-like cells in adults,” said Dr. Mariusz Ratjczak, leader of the research team and Director of the Stem-Cell Biology Program at the University of Kentucky at Louisville’s James Graham Brown Cancer Center .


The University of Illinois says related discoveries have been announced by at least five other laboratories. The University of Illinois has identified a similar type of stem cell in human umbilical cord blood and described their findings in July at the annual meeting of the International Society of Stem Cell Research in Toronto .


German researchers publishing in Nature said sperm stem cells from adult mouse testis have the capacity to form other cells. And researchers at Mount Sinai School of Medicine in New York described promising cells in the adult mouse heart.


“Those are real solid confirmations,” said Arthur Caplan, a nationally known bioethicist at the University of Pennsylvania . “That’s exactly what you look for when you claim a breakthrough.”




                




 

Scientists Isolate and Culture Stem Cells from Placenta
In an article at ScientificAmerican.com, Nikhil Swaminathan writes:

After seven years of toiling, scientists at the Wake Forest University School of Medicine and Harvard School of Medicine report they have isolated stem cells from a new source: amniotic fluid. The researchers not only succeeded in separating the progenitor cells from the many cells residing in the watery fluid in the placenta surrounding an embryo but were also able to coax the cells to differentiate into muscle, bone, fat, blood vessel, liver, and nerve cells.

According to lead author Anthony Atala, Director of Wake Forest's Institute of Regenerative Medicine, 99% of the U.S. population could conceivably find genetic matches for tissue regeneration or engineered organs from just 100,000 amniotic fluid samples. In its research, the team isolated stem cells via amniocentesis - a common procedure performed about 16 weeks into pregnancy during which amniotic fluid is drawn to test for genetic disorders in a fetus, as well as from the placenta after birth...

It's been known for decades that there are cells in amniotic fluid," Atala says. "The embryo is constantly shedding all these cells, as it's developing, to the amniotic fluid. The baby's actually breathing in, swallowing the fluid, and it's all coming out through all the pores and gets trapped in the placenta."...

Atala says that ... the major advantage is that after two weeks of culturing AFS cells expand quickly, doubling every 36 hours so that they are a large supply. When compared with embryonic stem cells, AFS cells have two main advantages: First, no embryo needs to be harmed in harvesting the cells, sidestepping a major, hot-buttoned political issue. Also, as Atala points out, AFS cells will not form tumor cells, as the considerably more raw embryo-derived cells can...

Going forward, Atala plans to study therapeutic uses for the AFS cells as well as attempt to coax them to differentiate into the tissue found in the heart, pancreas, and kidneys... "We need to keep studying all these different cell types to see what works best for each application at the end."

Amniotic Fluid Stem Cells Developing into Tubular Kidney Structures in Culture

Creating new kidneys using novel stem cells harvested from amniotic fluid is the ambitious, long-range goal of The Saban Research Institute laboratory of Roger De Filippo, MD.


Only two labs in the country are working with amniotic stem cells in this capacity, the second being that of Dr. Anthony Atala, with whom Dr. De Filippo completed a three-year fellowship at Children's Hospital Boston, Harvard Medical School.

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